Biologic Behaviour
•FSA is the 3rd most common primary bone neoplasm (5%-9%)
•FSA should be differentiated from fibroblastic OSA
•30%-40% FSA occur in the appendicular skeleton
•FSA may be endosteal (common) or parosteal
•parosteal may represent STS with extension into adjacent bone
•appendicular FSA is less malignant than oral FSA and slower to metastasize than appendicular OSA
•pathologic fracture 50%
•radiographic findings: usually lytic but occasionally can resemble OSA
•metastatic sites include heart, pericardium, skin, and other bones, but lungs are an uncommon metastatic site
•treatment: surgical resection is recommended, but role of chemotherapy is unknown
•12-month survival rate 29% with limb-sparing surgery and 66% after limb amputation
SURGICAL ONCOLOGY
SOCIETY
RESEARCH
EDUCATION
LINKS
EMPLOYMENT
FIBROSARCOMA
T0
No evidence of neoplasia
T1
Tumor confined within the medulla and cortex
Primary Tumor
T2
Tumor extends beyond the periosteum
M0
No evidence of lymph node involvement
M1
Evidence of distant metastasis with site specified
Metastasis