General Considerations
•synonyms: rodent ulcer and indolent ulcer
•eosinophilic granuloma is most common in female cats with a mean age of 5 years
•etiology unknown
•location: upper lip near midline is most common but can occur anywhere in the oral cavity
•slowly progressive (months to years) erosion of the lip
•biopsy required to differentiate from oral cancers
•treatment: prednisone (1-2 mg/kg q 12 hours for 30 days), methylprednisolone acetate (20 mg SC q 2 weeks), megestrol acetate, hypoallergenic diets, radiation therapy, surgery, immunomodulation, or cryosurgery
•prognosis: fair for complete and permanent recovery
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ORAL EOSINOPHILIC GRANULOMA